All concepts, explanations, trials, and studies have been re-written in plain English and may contain errors. I am not a doctor ----------------------------------------------------------- Related to: http://www.chfpatients.com/CHF.htm#CHF_case_example_2 ABLATION A 42 year old woman was referred to us for heart transplant. She had a 10 month history of heart failure with class 4 symptoms. An echo done in may of that year showed an ejection fraction of 45% ; in July it was 30% ; and in August it was 15%. A cath showed clear arteries. The decision was made that she needed a heart transplant. She and her family requested a second opinion here. When we saw her she was very, very ill. After reviewing her huge medical record and after interviewing her, the following points were known: 1) She had a 30 year history of bad bronchial asthma. She was on multiple meds because of her severe asthma. 2) She had a 4 year history of recurring a-fib. She had been treated with quinidine and developed ventricular fibrillation. About the time she started getting sicker, she went into chronic a-fib and her heart rate was under 140 - it was usually 160 beats per minute. What could we give this woman to control her heart rate? With her asthma, beta-blockers were not a good idea. She had a digoxin level of 2.2, so we could not increase that. So what did we do? We did an AV node ablation and implanted a pacemaker. Her response? Within a week her ejection fraction averaged 30% and 9 months later it was 45%. At her last visit, it was 55% and she had no more symptoms. This is certainly a better outcome and at a lower risk than going through a heart transplant!