All concepts, explanations, trials, and studies have been re-written in plain English and may contain errors. I am not a doctor ----------------------------------------------------------- Bundle branch block by John T. Lohr Bundle branch block (BBB) is a disruption in the normal flow of electrical pulses that drive the heart beat. Bundle branch block belongs to a group of heart problems called Intraventricular Conduction Defects (IVCD). There are two bundle branches, right and left. The right bundle carries nerve impulses that cause contraction of the right ventricle (the lower chamber of the heart) and the left bundle carries nerve impulses that cause contraction of the left ventricle. The two bundles start together at a junction called the bundle of His. Nerve impulses come through the sinus node of the heart to the bundle of His and then move into the right and left bundle branches. Bundle branch block is a slowing or interruption of nerve impulses. A problem may exist in any of the three bundles. Patients with BBB are generally without symptoms unless the disease is severe enough to cause a complete infranodal A-V block and very slow heart rate. In patients with right bundle branch block (RBBB), the nerve impulse is conducted slowly or not at all. The right ventricle finally receives the impulse through muscle-to-muscle spread, outside the regular nerve pathway. This method of electrical transmission is slow and results in a delayed contraction of the right ventricle. There are several types of left bundle branch block (LBBB), each different. In every case, the nerve impulse is blocked or delayed. Patients with LBBB may have left ventricular disease or cardiomyopathy. Left bundle branch block is usually caused by another disease, such as clogged arteries, rheumatic fever, congenital heart disease, myocarditis, or heart attack. Right bundle branch block happens less often from an underlying heart disease. Detection of BBB usually happens during a normal physical exam. The block shows up as a widening of the second heart sound. BBB is then confirmed through electrocardiogram (EKG). The EKG will show pulses in the heart beat and their length. A QRS lasting longer than 110 milliseconds indicates BBB. There is a unique EKG pattern for blocks in each of the 3 bundles. There is no specific therapy for BBB. Patients are usually treated for associated heart diseases. Prognosis for a person with blockage in any of the 3 bundle branches depends on the associated heart disease. The associated diseases determine the outcome of the patient's health. Occasionally, disruptions in bundle branches lead to complete infranodal A-V block, a more serious blockage of nerve impulses. About 2% of patients with BBB develop infranodal A-V blockage and these patients often require implanted pacemakers. Definition: QRS: A pattern seen in an electrocardiogram that indicates the pulses in a heart beat and their duration. Variations from a normal QRS pattern indicate heart disease. Source: 1999 Gale Research, Inc.