All concepts, explanations, trials, and studies have been
re-written in plain English and may contain errors. I am
not a doctor
-----------------------------------------------------------

NOTE: You can make the print bigger with the font button
on your browser! (It's usually a big "A")

-----------------------------------------------------------

Celebrex Safest Anti-inflammatory Drug For CHFers

May 28, 2004 - 	NSAIDs are often used by older people to
reduce arthritis symptoms, but increase risk of CHF. A
Canadian study shows that the COX2 inhibitor or "super
aspirin" Celebrex (celecoxib) is less likely to trigger
heart failure than other NSAIDs.
	Muhammad Mamdani analyzed previous studies - this
was not an actual new trial. Risk of hospital admission for
heart failure was the study endpoint.
	The study included records of 14,500 people using
the COX2 inhibitor Vioxx (rofecoxib), 19,000 using Celebrex,
and 5400 people taking non-selective NSAIDs. The control
group was 100,000 people not using NSAIDs.
	Compared with non-NSAID users, patients on Vioxx
had an 80% increase in hospital admission for CHF. People
using non-selective NSAIDS had 40% increased admission
risk. Celebrex users had the same rate of hospital
admission for CHF as people not taking NSAIDs.

Source: Intelihealth, The Lancet.